B3GNTL1

Across TCGA cell cohorts, B3GNTL1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible B3GNTL1-associated genes across cancer lineages are MT1B, TAS2R7, and CER1. Each is linked with B3GNTL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNTL1-to-partner and partner-to-B3GNTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT1B grouped by B3GNTL1-low versus B3GNTL1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNTL1→partner) and Y-score (partner→B3GNTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MT1B →	+0.128	+5.415	<.001	.004	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.021	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	CER1 →	+0.024	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	LRRC3B →	+0.030	+4.350	.003	.005	3	1
BLOOD_Lymphoma	OR52E4 →	+0.034	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	OR10T2 →	+0.031	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MT1B by B3GNTL1 expression — SKIN

Explore this box plot interactively →