B3GNT5

Across TCGA patient cohorts, B3GNT5 mutation is significantly associated with the RNA expression of many other genes, with 2,468 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNT5-associated genes across cancer lineages are IGKV1D-13, SLC25A15P4, and RN7SKP221. Each is linked with B3GNT5 in more than 2 cancer types. Because this analysis shows association rather than direction, both B3GNT5-to-partner and partner-to-B3GNT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGKV1D-13 grouped by B3GNT5-low versus B3GNT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT5→partner) and Y-score (partner→B3GNT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1D-13 →	+0.847	+1.990	.007	.002	3	3
LIHC	SLC25A15P4 →	+0.588	+5.119	<.001	.001	3	2
BRCA	RN7SKP221 →	+0.099	+8.471	<.001	.005	3	2
UCEC	TUBGCP5 →	+0.374	+1.664	<.001	<.001	3	2
UCEC	UHRF1 →	+0.761	+1.642	<.001	<.001	3	2
UCEC	RNVU1-28 →	+0.508	+1.423	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,468 associations by consensus.

IGKV1D-13 by B3GNT5 expression — UCEC

Explore this box plot interactively →