B3GNT5

Across TCGA patient cohorts, B3GNT5 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNT5-associated genes across cancer lineages are FASN, MEK1, and 4E-BP1. Each is linked with B3GNT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT5-to-partner and partner-to-B3GNT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by B3GNT5-low versus B3GNT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT5→partner) and Y-score (partner→B3GNT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.264	+1.440	.026	.022	3	2
UCEC	MEK1 →	+0.386	+2.999	<.001	<.001	3	2
UCEC	4E-BP1 →	+0.316	+4.087	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.082	-1.821	.006	.007	3	1
UCEC	A-Raf_pS299 →	-0.117	-1.652	.001	.005	3	1
UCEC	ACC_pS79 →	+0.257	+1.321	.014	.012	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

FASN by B3GNT5 expression — UCEC

Explore this box plot interactively →