B3GNT5

Across TCGA cell cohorts, B3GNT5 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B3GNT5-associated genes across cancer lineages are CCDC54, UTF1, and REG1B. Each is linked with B3GNT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT5-to-partner and partner-to-B3GNT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC54 grouped by B3GNT5-low versus B3GNT5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT5→partner) and Y-score (partner→B3GNT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC54 →	+0.124	+3.736	<.001	.004	3	1
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1
LARGE_INTESTINE	REG1B →	+3.373	+3.518	<.001	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	HMX3 →	+0.568	+3.531	<.001	.007	3	1
LARGE_INTESTINE	USP17L7 →	+0.065	+3.333	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

CCDC54 by B3GNT5 expression — LARGE_INTESTINE

Explore this box plot interactively →