B3GNT2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, B3GNT2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B3GNT2-associated genes across cancer lineages are ACER1, SLC4A1, and CFHR2. Each is linked with B3GNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT2-to-partner and partner-to-B3GNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by B3GNT2-low versus B3GNT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT2→partner) and Y-score (partner→B3GNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEACER1 →+0.087+3.823.002.00631
LARGE_INTESTINESLC4A1 →+0.032+3.658.009.00531
LARGE_INTESTINECFHR2 →+0.038+4.022<.001.00631
LARGE_INTESTINEBEND4 →+0.300+3.807<.001.00621
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ACER1 by B3GNT2 expression — LARGE_INTESTINE

Box plot of ACER1 in B3GNT2-low vs B3GNT2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration