B3GLCT

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GLCT mutation is significantly associated with the RNA expression of many other genes, with 2,970 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GLCT-associated genes across cancer lineages are METTL17, PDP2, and BAG1. Each is linked with B3GLCT in more than 2 cancer types. Because this analysis shows association rather than direction, both B3GLCT-to-partner and partner-to-B3GLCT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GLCT→partner) and Y-score (partner→B3GLCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMETTL17 →+0.409+3.321.001<.00133
UCECPDP2 →+0.577+2.234<.001.00133
UCECBAG1 →+0.482+3.595<.001.00133
UCECHSBP1 →+0.390+3.708.003<.00133
UCECRPL26P29 →+0.358+2.169.005.00332
COADMTCO1P56 →+0.182+4.109<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,970 associations by consensus.

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