Across TCGA patient cohorts, B3GLCT mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GLCT-associated genes across cancer lineages are GATA6, Notch1, and C-Raf. Each is linked with B3GLCT in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GLCT-to-partner and partner-to-B3GLCT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GLCT→partner) and Y-score (partner→B3GLCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GATA6 →	-0.163	-2.000	.007	.030	3	2
UCEC	Notch1 →	+0.179	+2.594	<.001	.006	3	2
UCEC	C-Raf →	+0.185	+2.222	<.001	.010	3	2
UCEC	Heregulin →	-0.109	-1.700	.022	.042	3	1
UCEC	JNK_pT183_Y185 →	-0.188	-2.000	.003	.029	3	1
UCEC	Ku80 →	+0.256	+2.100	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

B3GLCT survival (RNA) · tumor vs normal (RNA) · all B3GLCT data types