Across TCGA cell cohorts, B3GLCT mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B3GLCT-associated genes across cancer lineages are C10orf53, ETDC, and SH3GL2. Each is linked with B3GLCT in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GLCT-to-partner and partner-to-B3GLCT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GLCT→partner) and Y-score (partner→B3GLCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C10orf53 →	+0.035	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ETDC →	+0.847	+5.209	<.001	.005	3	1
LARGE_INTESTINE	SH3GL2 →	+1.324	+3.252	<.001	.009	3	1
LARGE_INTESTINE	SERAC1 →	+0.659	+3.067	.005	.009	3	1
LARGE_INTESTINE	HRH4 →	+0.049	+3.432	.009	.005	3	1
LARGE_INTESTINE	CHMP7 →	+0.870	+3.064	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

B3GLCT survival (RNA) · tumor vs normal (RNA) · all B3GLCT data types