B3GAT3

Across TCGA pan-cancer cohorts, B3GAT3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated B3GAT3 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher B3GAT3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated B3GAT3 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, PDAC, and GBM are the cancer types where B3GAT3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	III,IV	0.314	0.753	.001	49	view →
PDAC	DFS	Quartile	All	0.275	0.473	.017	16	view →
GBM	OS	Quartile	All	0.338	0.580	.006	9	view →
HNSC	DFS	Median	II,III,IV	0.986	0.904	.035	2	view →
LUAD	DFS	Median	All	0.489	0.722	.031	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

B3GAT3–CCRCC (DFS)

Open the CCRCC breakdown →