B3GAT3

Across TCGA patient cohorts, B3GAT3 mutation is significantly associated with the RNA expression of many other genes, with 230 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GAT3-associated genes across cancer lineages are NR1H5P, ZNF734P, and FAM30C. Each is linked with B3GAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GAT3-to-partner and partner-to-B3GAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NR1H5P grouped by B3GAT3-low versus B3GAT3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GAT3→partner) and Y-score (partner→B3GAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NR1H5P →	+0.128	+4.721	<.001	.004	3	2
LUAD	ZNF734P →	+0.133	+3.572	.002	.007	3	2
LUAD	FAM30C →	+0.075	+4.315	<.001	.007	3	2
HNSC	SNORD114-28 →	+0.437	+5.505	<.001	.004	3	1
HNSC	RN7SKP181 →	+0.119	+5.182	.001	.007	3	1
HNSC	RN7SKP3 →	+0.105	+5.435	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 230 associations by consensus.

NR1H5P by B3GAT3 expression — COAD

Explore this box plot interactively →