B3GAT3

Across TCGA patient cohorts, B3GAT3 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GAT3-associated genes across cancer lineages are PCNA, E-Cadherin, and mTOR. Each is linked with B3GAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GAT3-to-partner and partner-to-B3GAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by B3GAT3-low versus B3GAT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GAT3→partner) and Y-score (partner→B3GAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.327	+3.000	.008	.037	3	1
UCEC	E-Cadherin →	-0.597	-3.000	.034	.037	3	1
UCEC	mTOR →	-0.275	-3.000	.003	.037	2	1
UCEC	Notch1 →	+0.206	+3.000	.011	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PCNA by B3GAT3 expression — UCEC

Explore this box plot interactively →