B3GAT2

Across TCGA patient cohorts, B3GAT2 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GAT2-associated genes across cancer lineages are Caspase-7-cleavedD198, A-Raf_pS299, and FOXO3a_pS318_S321. Each is linked with B3GAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GAT2-to-partner and partner-to-B3GAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by B3GAT2-low versus B3GAT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GAT2→partner) and Y-score (partner→B3GAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.718	+3.479	.002	.002	3	2
UCEC	A-Raf_pS299 →	-0.111	-2.000	.020	.030	3	1
UCEC	FOXO3a_pS318_S321 →	-0.129	-2.212	.009	.010	3	1
UCEC	ACC1 →	+0.465	+3.472	.001	.002	3	1
UCEC	Ku80 →	+0.205	+1.498	.031	.036	3	1
UCEC	Shc_pY317 →	-0.124	-2.584	.041	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Caspase-7-cleavedD198 by B3GAT2 expression — UCEC

Explore this box plot interactively →