B3GAT2

Across TCGA cell cohorts, B3GAT2 mutation is significantly associated with the RNA expression of many other genes, with 765 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B3GAT2-associated genes across cancer lineages are MAGEB4, SPACA1, and OR10A6. Each is linked with B3GAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GAT2-to-partner and partner-to-B3GAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by B3GAT2-low versus B3GAT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GAT2→partner) and Y-score (partner→B3GAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.008	+2.830	.001	.004	3	2
STOMACH	SPACA1 →	+0.023	+5.285	<.001	.003	3	1
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CFHR2 →	+0.395	+5.539	<.001	.003	3	1
LARGE_INTESTINE	TNRC6B →	+0.817	+3.502	<.001	.001	3	1
LARGE_INTESTINE	SGSM3 →	+0.776	+3.502	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 765 associations by consensus.

MAGEB4 by B3GAT2 expression — LARGE_INTESTINE

Explore this box plot interactively →