B3GAT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GAT1 mutation is significantly associated with the RNA expression of many other genes, with 3,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GAT1-associated genes across cancer lineages are RNA5SP369, MIR649, and ACBD5. Each is linked with B3GAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both B3GAT1-to-partner and partner-to-B3GAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP369 grouped by B3GAT1-low versus B3GAT1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GAT1→partner) and Y-score (partner→B3GAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNA5SP369 →+0.376+5.539<.001.00433
LUADMIR649 →+0.933+5.198<.001.00133
UCECACBD5 →+0.391+1.947.007<.00133
UCECSFXN1 →+0.452+2.532<.001<.00133
UCECIER3IP1 →+0.455+3.223<.001<.00133
UCECDDB2 →+0.587+2.807<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,132 associations by consensus.

RNA5SP369 by B3GAT1 expression — CESC

Box plot of RNA5SP369 in B3GAT1-low vs B3GAT1-high samples in CESC.

Explore this box plot interactively →

Exploration