B3GAT1

Across TCGA patient cohorts, B3GAT1 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GAT1-associated genes across cancer lineages are ACC1, eIF4E, and MSH6. Each is linked with B3GAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both B3GAT1-to-partner and partner-to-B3GAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by B3GAT1-low versus B3GAT1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GAT1→partner) and Y-score (partner→B3GAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ACC1 →	+0.408	+3.000	.011	.034	3	3
UCEC	eIF4E →	+0.150	+2.183	.030	.033	3	2
UCEC	MSH6 →	-0.355	-1.807	.001	.024	3	2
COAD	PCNA →	+0.276	+3.178	.023	.010	3	2
UCEC	AMPK_pT172 →	+0.266	+1.874	.049	.049	3	2
UCEC	Annexin-1 →	+0.615	+2.999	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

ACC1 by B3GAT1 expression — SKCM

Explore this box plot interactively →