B3GAT1

Across TCGA cell cohorts, B3GAT1 mutation is significantly associated with the RNA expression of many other genes, with 187 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B3GAT1-associated genes across cancer lineages are DCD, CRYGC, and PRORY. Each is linked with B3GAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GAT1-to-partner and partner-to-B3GAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCD grouped by B3GAT1-low versus B3GAT1-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GAT1→partner) and Y-score (partner→B3GAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DCD →	+0.046	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	CRYGC →	+0.083	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	PRORY →	+0.536	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	RPS4Y2 →	+0.080	+4.643	<.001	.008	3	1
STOMACH	GZMA →	+0.084	+3.584	<.001	.009	3	1
STOMACH	SPHKAP →	+0.008	+3.432	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 187 associations by consensus.

DCD by B3GAT1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →