Across TCGA patient cohorts, B3GALT5 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALT5-associated genes across cancer lineages are ERK2, 14-3-3_beta, and EGFR_pY1068. Each is linked with B3GALT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GALT5-to-partner and partner-to-B3GALT5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALT5→partner) and Y-score (partner→B3GALT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.260	+3.321	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.079	-1.847	.036	.049	3	1
UCEC	EGFR_pY1068 →	-0.276	-3.584	.003	.002	3	1
UCEC	EGFR →	-0.159	-1.415	.008	.046	3	1
UCEC	JNK2 →	+0.160	+2.009	.032	.017	3	1
UCEC	MEK1 →	+0.283	+2.807	.039	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

B3GALT5 survival (RNA) · tumor vs normal (RNA) · all B3GALT5 data types