B3GALT1

Across TCGA patient cohorts, B3GALT1 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALT1-associated genes across cancer lineages are Caspase-7-cleavedD198, HER2, and Ku80. Each is linked with B3GALT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both B3GALT1-to-partner and partner-to-B3GALT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by B3GALT1-low versus B3GALT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALT1→partner) and Y-score (partner→B3GALT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.601	+1.785	.002	.007	3	3
SKCM	HER2 →	+0.308	+2.000	.015	.031	3	2
UCEC	Ku80 →	+0.277	+1.887	<.001	.001	3	2
UCEC	MEK1 →	+0.364	+1.874	.002	.002	3	2
UCEC	Notch1 →	+0.191	+2.201	<.001	<.001	3	2
UCEC	Src_pY527 →	-0.378	-2.115	.008	.016	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Caspase-7-cleavedD198 by B3GALT1 expression — UCEC

Explore this box plot interactively →