B3GALT1-AS1

Across TCGA pan-cancer cohorts, B3GALT1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated B3GALT1-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher B3GALT1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated B3GALT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and ESCA show a favorable association.

COAD, KICH, and LUSC are the cancer types where B3GALT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	III,IV	0.466	0.709	.001	84	view →
KICH	DFS	Tertile	III,IV	0.285	1.000	.004	48	view →
LUSC	OS	Median	All	0.825	0.701	<.001	40	view →
ACC	OS	Tertile	All	0.603	0.873	.004	36	view →
STAD	DFS	Tertile	IV	0.163	1.000	<.001	30	view →
ESCA	OS	Median	II,III,IV	0.788	0.580	.004	26	view →
LGG	DFS	Median	All	0.669	0.791	<.001	26	view →
KIRC	DFS	Quartile	All	0.636	0.822	.003	22	view →
SKCM	DFS	Tertile	All	0.264	0.148	.002	19	view →
CESC	OS	Tertile	All	0.868	0.757	.014	18	view →
THCA	OS	Tertile	IV	0.510	0.873	.013	15	view →
SARC	OS	Quartile	All	0.618	0.813	<.001	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

B3GALT1-AS1–COAD (DFS)

Open the COAD breakdown →