B3GALNT2

Across TCGA pan-cancer cohorts, B3GALNT2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated B3GALNT2 data layer compared with 24 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher B3GALNT2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated B3GALNT2 expression acts as an unfavorable survival marker.

LIHC, SCLC, and PRAD are the cancer types where B3GALNT2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.093	0.783	<.001	30	view →
SCLC	OS	Median	All	0.219	0.706	.011	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

B3GALNT2–LIHC (OS)

Open the LIHC breakdown →