B3GALNT1

Across TCGA patient cohorts, B3GALNT1 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALNT1-associated genes across cancer lineages are STAT5a, 14-3-3_beta, and A-Raf_pS299. Each is linked with B3GALNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GALNT1-to-partner and partner-to-B3GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT5a grouped by B3GALNT1-low versus B3GALNT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALNT1→partner) and Y-score (partner→B3GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT5a →	+0.401	+3.169	.015	.019	3	2
UCEC	14-3-3_beta →	-0.121	-1.794	.003	.027	3	1
UCEC	A-Raf_pS299 →	-0.153	-2.321	.001	.006	3	1
UCEC	Gab2 →	+0.330	+1.807	.025	.027	3	1
UCEC	Heregulin →	-0.128	-1.807	.012	.027	3	1
UCEC	IGFBP2 →	-0.704	-1.807	.008	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

STAT5a by B3GALNT1 expression — UCEC

Explore this box plot interactively →