AZIN1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AZIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 115 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AZIN1-associated genes across cancer lineages are SHROOM2, MTDH, and NTAN1. Each is linked with AZIN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AZIN1-to-partner and partner-to-AZIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AZIN1 versus SHROOM2 in GBM, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZIN1→partner) and Y-score (partner→AZIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSHROOM2 →-1.666-1.050.008.00631
GBMMTDH →-0.303-1.363.005.00731
GBMNTAN1 →-0.303-1.050.007.00531
GBMRSPO1 →+0.193+1.050.002.00531
GBMTTTY13 →+0.100+1.159.004.00431
GBMMIR383 →+1.803+1.155.009.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

AZIN1 vs SHROOM2 — GBM

Per-sample scatter of AZIN1 vs SHROOM2 in GBM (Pearson r = -0.73).

Explore this scatter interactively →

Exploration