AZIN1

Across TCGA cell cohorts, AZIN1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AZIN1-associated genes across cancer lineages are MTRNR2L10, UTF1, and REG1B. Each is linked with AZIN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AZIN1-to-partner and partner-to-AZIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTRNR2L10 grouped by AZIN1-low versus AZIN1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZIN1→partner) and Y-score (partner→AZIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MTRNR2L10 →	+0.016	+6.357	<.001	<.001	3	1
LARGE_INTESTINE	UTF1 →	+0.018	+3.632	<.001	.003	3	1
LARGE_INTESTINE	REG1B →	+3.374	+3.196	<.001	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.016	+3.977	<.001	.001	3	1
LARGE_INTESTINE	FAM218A →	+0.430	+3.906	<.001	.002	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MTRNR2L10 by AZIN1 expression — CNS

Explore this box plot interactively →