AZI2

Across TCGA patient cohorts, AZI2 RNA expression is significantly associated with the mutation status of many other genes, with 9,905 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AZI2-associated genes across cancer lineages are TP53, MYH6, and DNAH5. Each is linked with AZI2 in more than 4 cancer types. Because this analysis shows association rather than direction, both AZI2-to-partner and partner-to-AZI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by AZI2-low versus AZI2-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZI2→partner) and Y-score (partner→AZI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TP53 →	+1.504	+0.449	.001	<.001	3	5
STAD	MYH6 →	+2.165	+0.318	.008	.003	3	5
UCEC	DNAH5 →	+1.021	+0.334	<.001	<.001	3	5
STAD	NIPBL →	+3.601	+0.391	.001	<.001	3	4
STAD	EVPL →	+2.601	+0.391	.006	.004	2	5
LGG	CIC →	+1.772	+0.171	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,905 associations by consensus.

TP53 by AZI2 expression — SKCM

Explore this box plot interactively →