AZI2

Across TCGA cell cohorts, AZI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,376 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AZI2-associated GO terms across cancer lineages are Microtubule polymerization, Retrograde transport, endosome to Golgi, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with AZI2 in more than 14 cancer types. Because this analysis shows association rather than direction, both AZI2-to-partner and partner-to-AZI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by AZI2-low versus AZI2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AZI2→partner) and Y-score (partner→AZI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule polymerization →	+0.105	+0.574	<.001	<.001	3	15
SOFT_TISSUE	Retrograde transport, endosome to Golgi →	+0.070	+0.971	<.001	<.001	3	14
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.088	+0.725	<.001	<.001	3	14
LARGE_INTESTINE	Negative regulation of wound healing, spreading of epidermal cells →	+0.146	+0.725	<.001	<.001	3	14
BONE	Cytosolic transport →	+0.070	+0.612	<.001	<.001	3	13
BREAST	Negative regulation of microtubule depolymerization →	+0.091	+0.615	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,376 associations by consensus.

Microtubule polymerization by AZI2 expression — LARGE_INTESTINE

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