AZGP1

Across TCGA pan-cancer cohorts, AZGP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AZGP1 data layer compared with 24 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher AZGP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated AZGP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD, CCRCC, and UCEC are the cancer types where AZGP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	III,IV	0.368	0.957	.003	40	view →
CCRCC	DFS	Median	All	0.864	0.627	.005	36	view →
UCEC	DFS	Tertile	II,III,IV	0.535	1.000	.008	24	view →
LSCC	DFS	Tertile	II,III,IV	0.787	1.000	.003	14	view →
HNSC	OS	Median	II,III,IV	0.952	1.000	.016	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AZGP1–LUAD (DFS)

Open the LUAD breakdown →