AZGP1

Across TCGA patient cohorts, AZGP1 mutation is significantly associated with the RNA expression of many other genes, with 1,313 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AZGP1-associated genes across cancer lineages are LINC02647, RNA5SP480, and RRP12. Each is linked with AZGP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AZGP1-to-partner and partner-to-AZGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02647 grouped by AZGP1-low versus AZGP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZGP1→partner) and Y-score (partner→AZGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02647 →	+0.294	+7.640	<.001	.009	3	2
BLCA	RNA5SP480 →	+0.583	+7.640	<.001	.009	3	2
UCEC	RRP12 →	+0.408	+2.593	.007	.006	3	2
COAD	MIR2467 →	+0.816	+5.081	<.001	.001	3	2
SKCM	FTH1P15 →	+0.584	+3.465	.003	.003	3	2
SKCM	MTCO1P52 →	+0.020	+4.163	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,313 associations by consensus.

LINC02647 by AZGP1 expression — BLCA

Explore this box plot interactively →