AXL

Across TCGA cell cohorts, AXL protein abundance is significantly associated with the RNA expression of many other genes, with 3,691 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AXL-associated genes across cancer lineages are VIM, PMP22, and FAM117A. Each is linked with AXL in more than 9 cancer types. Because this analysis shows association rather than direction, both AXL-to-partner and partner-to-AXL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AXL versus VIM in SOFT_TISSUE, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AXL→partner) and Y-score (partner→AXL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	VIM →	+2.817	+2.510	.003	<.001	3	10
BONE	PMP22 →	+4.668	+2.452	.001	<.001	3	6
BONE	FAM117A →	-1.510	-1.934	.007	.002	3	5
BREAST	EMP3 →	+4.360	+3.590	.002	.002	3	5
BONE	MED7 →	+0.731	+1.761	.002	.005	3	5
BREAST	CDS1 →	-1.878	-2.915	.009	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

AXL vs VIM — SOFT_TISSUE

Explore this scatter interactively →