AXL

Across TCGA cell cohorts, AXL protein abundance is significantly associated with the go_rna of many other GO terms, with 2,079 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AXL-associated GO terms across cancer lineages are Long-term synaptic potentiation, Phagocytosis, and Negative regulation of cell adhesion. Each is linked with AXL in more than 3 cancer types. Because this analysis shows association rather than direction, both AXL-to-partner and partner-to-AXL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Long-term synaptic potentiation grouped by AXL-low versus AXL-high in KIDNEY.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AXL→partner) and Y-score (partner→AXL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Long-term synaptic potentiation →	+0.100	+1.478	.003	.002	3	4
BONE	Phagocytosis →	+0.080	+1.671	.002	.008	3	4
BONE	Negative regulation of cell adhesion →	+0.118	+2.342	.001	.001	3	4
BONE	ATP transport →	-0.115	-2.212	.001	<.001	3	4
BONE	Glycosyl compound catabolic process →	+0.161	+1.832	<.001	.002	3	4
BONE	Protein localization to early endosome →	+0.266	+1.984	.006	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,079 associations by consensus.

Long-term synaptic potentiation by AXL expression — KIDNEY

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