AXDND1

Across TCGA patient cohorts, AXDND1 mutation is significantly associated with the RNA expression of many other genes, with 5,318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AXDND1-associated genes across cancer lineages are CDKN3, ADNP2, and NCAPG. Each is linked with AXDND1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AXDND1-to-partner and partner-to-AXDND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDKN3 grouped by AXDND1-low versus AXDND1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AXDND1→partner) and Y-score (partner→AXDND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDKN3 →	+0.629	+1.844	<.001	<.001	3	4
LUAD	ADNP2 →	+0.581	+2.906	<.001	.001	3	4
UCEC	NCAPG →	+0.545	+1.283	.001	.005	3	4
SKCM	STIL →	+0.403	+1.593	.004	.001	3	4
UCEC	NUSAP1 →	+0.628	+1.562	<.001	.002	3	4
UCEC	DTL →	+0.471	+1.601	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,318 associations by consensus.

CDKN3 by AXDND1 expression — UCEC

Explore this box plot interactively →