Across TCGA patient cohorts, AWAT1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AWAT1-associated genes across cancer lineages are A-Raf_pS299, ERK2, and JNK2. Each is linked with AWAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AWAT1-to-partner and partner-to-AWAT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AWAT1→partner) and Y-score (partner→AWAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.131	-3.000	.019	.036	3	1
UCEC	ERK2 →	+0.181	+2.584	.043	.011	3	1
UCEC	JNK2 →	+0.297	+3.331	.001	.005	3	1
UCEC	Notch1 →	+0.145	+2.820	.027	.035	3	1
UCEC	PCNA →	+0.246	+2.584	.014	.011	3	1
UCEC	PDCD4 →	-0.525	-2.990	.016	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

AWAT1 survival (RNA) · tumor vs normal (RNA) · all AWAT1 data types