Across TCGA cell cohorts, AWAT1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AWAT1-associated genes across cancer lineages are OR2M5, OR4F4, and CCDC172. Each is linked with AWAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AWAT1-to-partner and partner-to-AWAT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AWAT1→partner) and Y-score (partner→AWAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2M5 →	+0.016	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR4F4 →	+0.017	+4.273	.001	.006	3	1
LARGE_INTESTINE	CCDC172 →	+0.004	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ELOA3DP →	+0.026	+4.273	<.001	.006	3	1
LARGE_INTESTINE	PPIAL4E →	+0.049	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OR6Q1 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

AWAT1 survival (RNA) · tumor vs normal (RNA) · all AWAT1 data types