Across TCGA cell cohorts, AWAT1 mutation is significantly associated with the mutation status of many other genes, with 530 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AWAT1-associated genes across cancer lineages are OR51I2, MESP2, and ZNF559. Each is linked with AWAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AWAT1-to-partner and partner-to-AWAT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AWAT1→partner) and Y-score (partner→AWAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR51I2 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	MESP2 →	+3.672	+4.799	.002	.002	1	1
LARGE_INTESTINE	ZNF559 →	+2.865	+4.217	.007	.007	1	1
LARGE_INTESTINE	CERKL →	+2.865	+4.217	.007	.007	1	1
LARGE_INTESTINE	RTL6 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	SLC4A5 →	+3.087	+4.392	.005	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 530 associations by consensus.

Exploration

AWAT1 survival (RNA) · tumor vs normal (RNA) · all AWAT1 data types