AVPR2

Across TCGA patient cohorts, AVPR2 mutation is significantly associated with the RNA expression of many other genes, with 2,485 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AVPR2-associated genes across cancer lineages are RN7SKP250, RN7SL591P, and TTC22. Each is linked with AVPR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AVPR2-to-partner and partner-to-AVPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP250 grouped by AVPR2-low versus AVPR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPR2→partner) and Y-score (partner→AVPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP250 →	+0.271	+5.136	<.001	.002	3	2
COAD	RN7SL591P →	+0.328	+4.807	<.001	.004	3	2
UCEC	TTC22 →	-0.843	-1.938	<.001	.001	3	2
UCEC	RNA5SP411 →	+0.820	+1.683	<.001	.002	3	2
LUAD	HNRNPA1P58 →	+0.143	+2.718	<.001	.004	3	2
LUAD	PCNPP2 →	+0.069	+4.333	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,485 associations by consensus.

RN7SKP250 by AVPR2 expression — COAD

Explore this box plot interactively →