AVPR2

Across TCGA cell cohorts, AVPR2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AVPR2-associated genes across cancer lineages are OR10W1, SPATA19, and WFDC12. Each is linked with AVPR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AVPR2-to-partner and partner-to-AVPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by AVPR2-low versus AVPR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPR2→partner) and Y-score (partner→AVPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.015	+4.977	<.001	.007	3	1
BLOOD_Leukemia	SPATA19 →	+0.022	+5.569	<.001	.001	3	1
BLOOD_Leukemia	WFDC12 →	+0.244	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR6B3 →	+0.016	+4.539	<.001	.007	3	1
BLOOD_Leukemia	WFDC11 →	+0.030	+4.539	<.001	.007	3	1
BLOOD_Leukemia	TRIM49B →	+0.158	+4.874	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR10W1 by AVPR2 expression — LARGE_INTESTINE

Explore this box plot interactively →