AVPI1

Across TCGA patient cohorts, AVPI1 protein abundance is significantly associated with the RNA expression of many other genes, with 153 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AVPI1-associated genes across cancer lineages are ACTL8, PGD, and NDUFB11. Each is linked with AVPI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AVPI1-to-partner and partner-to-AVPI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AVPI1 versus ACTL8 in GBM, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPI1→partner) and Y-score (partner→AVPI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACTL8 →	+0.720	+0.442	.003	.008	3	1
GBM	PGD →	+0.773	+0.493	.006	.001	3	1
GBM	NDUFB11 →	+0.557	+0.387	.006	.001	3	1
GBM	C11orf52 →	+0.255	+0.387	.005	.001	3	1
GBM	PMVK →	+0.939	+0.387	.003	.001	3	1
GBM	FCRL1 →	-0.150	-0.449	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 153 associations by consensus.

AVPI1 vs ACTL8 — GBM

Explore this scatter interactively →