AVPI1

Across TCGA cell cohorts, AVPI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,473 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AVPI1-associated GO terms across cancer lineages are Positive regulation of alpha-beta T cell proliferation, Zymogen activation, and Negative regulation of immune response. Each is linked with AVPI1 in more than 9 cancer types. Because this analysis shows association rather than direction, both AVPI1-to-partner and partner-to-AVPI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of alpha-beta T cell proliferation grouped by AVPI1-low versus AVPI1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPI1→partner) and Y-score (partner→AVPI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of alpha-beta T cell proliferation →	+0.228	+1.725	.001	<.001	3	10
BONE	Zymogen activation →	+0.316	+2.383	<.001	<.001	3	10
BREAST	Negative regulation of immune response →	+0.087	+0.868	.001	.002	3	9
OVARY	Sleep →	+1.410	+1.998	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Regulation of fever generation →	+1.903	+2.020	<.001	<.001	3	9
LUNG_SCLC	Cellular response to lipopolysaccharide →	+0.062	+1.129	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,473 associations by consensus.

Positive regulation of alpha-beta T cell proliferation by AVPI1 expression — OVARY

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