AVL9

Across TCGA cell cohorts, AVL9 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AVL9-associated genes across cancer lineages are S100A7A, OR11G2, and SIGLEC5. Each is linked with AVL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both AVL9-to-partner and partner-to-AVL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S100A7A grouped by AVL9-low versus AVL9-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVL9→partner) and Y-score (partner→AVL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	S100A7A →	+0.035	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	OR11G2 →	+0.016	+4.867	<.001	.009	3	1
BREAST	SIGLEC5 →	+0.015	+4.312	<.001	.001	3	1
BREAST	IL9 →	+0.032	+4.196	<.001	.006	3	1
LARGE_INTESTINE	PRM1 →	+0.314	+4.000	<.001	<.001	3	1
LARGE_INTESTINE	ARGFX →	+0.008	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

S100A7A by AVL9 expression — BLOOD_Lymphoma

Explore this box plot interactively →