AVIL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AVIL protein abundance is significantly associated with the protein abundance of many other proteins, with 9,091 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AVIL-associated proteins across cancer lineages are ANK1_T961, ANK3_S959, and SLCO2A1. Each is linked with AVIL in more than 1 cancer types. Because this analysis shows association rather than direction, both AVIL-to-partner and partner-to-AVIL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AVIL versus ANK1_T961 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AVIL→partner) and Y-score (partner→AVIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCANK1_T961 →+0.438+0.833<.001<.00132
HNSCANK3_S959 →+0.681+0.648<.001<.00132
PDACSLCO2A1 →+0.756+0.714<.001<.00132
PDACTC2N →+0.450+0.573<.001<.00132
LUADNUMA1_S1862 →-0.768-0.355.001.00132
LUADSGCD →+0.619+0.557.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,091 associations by consensus.

AVIL vs ANK1_T961 — HNSC

Per-sample scatter of AVIL vs ANK1_T961 in HNSC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration