AUTS2

Across TCGA patient cohorts, AUTS2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,140 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AUTS2-associated genes across cancer lineages are RNF144A, IRF1, and PXDN. Each is linked with AUTS2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AUTS2-to-partner and partner-to-AUTS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AUTS2 versus RNF144A in LUAD, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AUTS2→partner) and Y-score (partner→AUTS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNF144A →	+0.540	+0.515	<.001	<.001	3	3
UCEC	IRF1 →	-0.632	-0.419	.001	<.001	3	3
PDAC	PXDN →	+0.791	+0.410	.005	.001	3	2
PDAC	TTC9 →	+0.668	+0.369	.007	.005	3	2
PDAC	FAM167A →	+0.728	+0.403	.001	<.001	3	2
PDAC	SPRR1B →	+2.255	+0.390	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,140 associations by consensus.

AUTS2 vs RNF144A — LUAD

Explore this scatter interactively →