AUTS2

Across TCGA cell cohorts, AUTS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,986 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AUTS2-associated GO terms across cancer lineages are Regulation of G0 to G1 transition, Alpha-beta T cell activation, and Cysteine transmembrane transport. Each is linked with AUTS2 in more than 10 cancer types. Because this analysis shows association rather than direction, both AUTS2-to-partner and partner-to-AUTS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G0 to G1 transition grouped by AUTS2-low versus AUTS2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AUTS2→partner) and Y-score (partner→AUTS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of G0 to G1 transition →	+0.136	+3.093	<.001	<.001	3	11
BREAST	Alpha-beta T cell activation →	-0.106	-1.986	.001	.002	3	10
BREAST	Cysteine transmembrane transport →	-0.195	-1.880	.005	.005	3	9
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.103	+1.789	<.001	<.001	3	9
BREAST	Cysteine transport →	-0.195	-1.880	.005	.005	3	9
BLOOD_Leukemia	Positive regulation of lipid localization →	-0.060	-2.194	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,986 associations by consensus.

Regulation of G0 to G1 transition by AUTS2 expression — LUNG_SCLC

Explore this box plot interactively →