AURKB

Across TCGA cell cohorts, AURKB RNA expression is significantly associated with the go_rna of many other GO terms, with 5,200 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AURKB-associated GO terms across cancer lineages are Kinetochore assembly, Kinetochore organization, and Regulation of DNA-templated DNA replication. Each is linked with AURKB in more than 19 cancer types. Because this analysis shows association rather than direction, both AURKB-to-partner and partner-to-AURKB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Kinetochore assembly grouped by AURKB-low versus AURKB-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AURKB→partner) and Y-score (partner→AURKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Kinetochore assembly →	+0.176	+0.926	<.001	<.001	3	20
OESOPHAGUS	Kinetochore organization →	+0.176	+0.926	<.001	<.001	3	20
PANCREAS	Regulation of DNA-templated DNA replication →	+0.131	+1.290	<.001	<.001	3	20
PANCREAS	Cell cycle DNA replication initiation →	+0.212	+1.434	<.001	<.001	3	19
PANCREAS	Nuclear cell cycle DNA replication initiation →	+0.212	+1.434	<.001	<.001	3	19
PANCREAS	Mitotic DNA replication initiation →	+0.212	+1.434	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,200 associations by consensus.

Kinetochore assembly by AURKB expression — OESOPHAGUS

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