AURKAIP1

Across TCGA cell cohorts, AURKAIP1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AURKAIP1-associated genes across cancer lineages are KRT84, TCF21, and C20orf85. Each is linked with AURKAIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AURKAIP1-to-partner and partner-to-AURKAIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT84 grouped by AURKAIP1-low versus AURKAIP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AURKAIP1→partner) and Y-score (partner→AURKAIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KRT84 →	+0.547	+4.152	<.001	.009	3	2
BLOOD_Leukemia	TCF21 →	+0.013	+4.705	<.001	.003	3	1
BLOOD_Leukemia	C20orf85 →	+0.023	+4.969	<.001	.003	3	1
BLOOD_Leukemia	ART1 →	+0.022	+4.705	<.001	.003	3	1
BLOOD_Leukemia	PRR30 →	+0.032	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	OR10T2 →	+0.558	+4.276	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

KRT84 by AURKAIP1 expression — BLOOD_Leukemia

Explore this box plot interactively →