AURKA

Across TCGA patient cohorts, AURKA RNA expression is significantly associated with the protein abundance of many other proteins, with 25,717 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AURKA-associated proteins across cancer lineages are NCL_S67, NPM1_S254, and NPM1_T199. Each is linked with AURKA in more than 9 cancer types. Because this analysis shows association rather than direction, both AURKA-to-partner and partner-to-AURKA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AURKA versus NCL_S67 in LUAD, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AURKA→partner) and Y-score (partner→AURKA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCL_S67 →	+1.032	+1.130	<.001	<.001	3	10
BRCA	NPM1_S254 →	+1.149	+0.904	<.001	<.001	3	10
LUAD	NPM1_T199 →	+1.779	+0.836	<.001	<.001	3	10
GBM	OBI1_S210 →	+1.020	+0.925	<.001	<.001	3	10
LUAD	PAICS_S27 →	+1.466	+1.299	<.001	<.001	3	10
OV	PCNA →	+0.740	+1.276	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,717 associations by consensus.

AURKA vs NCL_S67 — LUAD

Explore this scatter interactively →