AUP1

Across TCGA pan-cancer cohorts, AUP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AUP1 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher AUP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated AUP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, OV, and CCRCC are the cancer types where AUP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	1.000	0.375	.006	20	view →
OV	DFS	Median	All	0.867	1.000	.038	4	view →
CCRCC	OS	Median	IV	0.150	0.785	.040	4	view →
HNSC	OS	Tertile	All	1.000	0.940	.030	4	view →
LUAD	OS	Median	III,IV	0.764	0.985	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AUP1–UCEC (OS)

Open the UCEC breakdown →