AUP1

Across TCGA cell cohorts, AUP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,393 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AUP1-associated GO terms across cancer lineages are Mitochondrial mRNA polyadenylation, Synaptic vesicle recycling via endosome, and Transcription initiation at RNA polymerase I promoter. Each is linked with AUP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both AUP1-to-partner and partner-to-AUP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial mRNA polyadenylation grouped by AUP1-low versus AUP1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AUP1→partner) and Y-score (partner→AUP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitochondrial mRNA polyadenylation →	+0.100	+0.483	.001	.001	3	11
SKIN	Synaptic vesicle recycling via endosome →	+0.064	+0.297	<.001	.005	3	10
BLOOD_Lymphoma	Transcription initiation at RNA polymerase I promoter →	+0.094	+0.528	<.001	.001	3	9
SOFT_TISSUE	Late viral transcription →	+0.093	+0.519	<.001	<.001	3	9
BREAST	Regulation of t-circle formation →	+0.100	+0.458	<.001	.001	3	8
BLOOD_Leukemia	Telomeric loop disassembly →	+0.054	+0.331	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,393 associations by consensus.

Mitochondrial mRNA polyadenylation by AUP1 expression — BLOOD_Lymphoma

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