AUNIP

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AUNIP mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AUNIP-associated genes across cancer lineages are Fibroblasts, CD8+ Tem, and Adipocytes. Each is linked with AUNIP in more than 1 cancer types. Because this analysis shows association rather than direction, both AUNIP-to-partner and partner-to-AUNIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by AUNIP-low versus AUNIP-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AUNIP→partner) and Y-score (partner→AUNIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCFibroblasts →+0.057+5.339<.001.04731
UCECCD8+ Tem →+0.004+5.066<.001.03331
UCECAdipocytes →+0.028+2.507.006.02231
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Fibroblasts by AUNIP expression — HNSC

Box plot of Fibroblasts in AUNIP-low vs AUNIP-high samples in HNSC.

Explore this box plot interactively →

Exploration