ATXN8OS

Across TCGA patient cohorts, ATXN8OS RNA expression is significantly associated with the go_rna of many other GO terms, with 6,499 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ATXN8OS-associated GO terms across cancer lineages are Mitochondrial electron transport, NADH to ubiquinone, Mitochondrial respiratory chain complex assembly, and Aerobic respiration. Each is linked with ATXN8OS in more than 7 cancer types. Because this analysis shows association rather than direction, both ATXN8OS-to-partner and partner-to-ATXN8OS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, NADH to ubiquinone grouped by ATXN8OS-low versus ATXN8OS-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN8OS→partner) and Y-score (partner→ATXN8OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.088	+0.027	<.001	<.001	3	8
STAD	Mitochondrial respiratory chain complex assembly →	+0.071	+0.024	<.001	<.001	3	8
STAD	Aerobic respiration →	+0.077	+0.024	<.001	<.001	3	8
STAD	Protein stabilization →	+0.063	+0.025	<.001	<.001	3	7
STAD	Vesicle localization →	+0.051	+0.026	<.001	<.001	3	7
LGG	Dendritic spine morphogenesis →	+0.041	+0.086	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,499 associations by consensus.

Mitochondrial electron transport, NADH to ubiquinone by ATXN8OS expression — STAD

Explore this box plot interactively →