ATXN7L3B

Across TCGA cell cohorts, ATXN7L3B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,566 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATXN7L3B-associated GO terms across cancer lineages are Positive regulation of myoblast differentiation, Positive regulation of mRNA metabolic process, and Regulation of nucleotide-excision repair. Each is linked with ATXN7L3B in more than 13 cancer types. Because this analysis shows association rather than direction, both ATXN7L3B-to-partner and partner-to-ATXN7L3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of myoblast differentiation grouped by ATXN7L3B-low versus ATXN7L3B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN7L3B→partner) and Y-score (partner→ATXN7L3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of myoblast differentiation →	+0.139	+0.667	<.001	.002	3	14
BLOOD_Lymphoma	Positive regulation of mRNA metabolic process →	+0.067	+0.872	<.001	<.001	3	13
BONE	Regulation of nucleotide-excision repair →	+0.126	+1.051	<.001	<.001	3	13
STOMACH	Negative regulation of transcription by RNA polymerase III →	+0.173	+0.829	<.001	.001	3	12
BONE	Regulatory ncRNA-mediated gene silencing →	+0.101	+1.301	<.001	<.001	3	12
OVARY	Regulation of DNA-templated transcription elongation →	+0.065	+0.672	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,566 associations by consensus.

Positive regulation of myoblast differentiation by ATXN7L3B expression — URINARY_TRACT

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