ATXN7L1

Across TCGA patient cohorts, ATXN7L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,210 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATXN7L1-associated proteins across cancer lineages are ATXN7L1_S38, CUX1_S1069, and GATAD2B. Each is linked with ATXN7L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATXN7L1-to-partner and partner-to-ATXN7L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN7L1 versus ATXN7L1_S38 in PDAC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN7L1→partner) and Y-score (partner→ATXN7L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ATXN7L1_S38 →	+0.572	+0.401	.003	<.001	1	6
HNSC	CUX1_S1069 →	+0.500	+0.511	<.001	<.001	3	4
LSCC	GATAD2B →	+0.318	+0.426	<.001	<.001	3	4
LSCC	PUS7 →	+0.482	+0.433	<.001	<.001	3	4
HNSC	HNRNPLL →	+0.299	+0.712	<.001	.001	3	4
GBM	WDR5 →	+0.209	+0.258	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,210 associations by consensus.

ATXN7L1 vs ATXN7L1_S38 — PDAC

Explore this scatter interactively →